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The effect of water-soluble polymers on aqueous solubility of drugs

✍ Scribed by Thorsteinn Loftsson; Hafrün Fri∂riksdóttir; Thrórunn K. Gu∂mundsdóttir

Book ID
113368142
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
271 KB
Volume
127
Category
Article
ISSN
0378-5173

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A new approach of improving drug dissolution properties is described. This method exploits the property of a carrier owing to the hydrotalcite-type anionic clays (HTlc). HTlc is an inorganic layered solid that lodges anionic compounds among its layers. As HTlc dissolves at acidic pH values (pH < 4),