The olfactory bulbectomized (OB) rat has been developed as an animal model of depression. In the novel `open ยฎeld' environment, OB rats showed a hyperactivity which was attenuated by chronic treatment with desipramine (7 . 5 mg/ kg) for 20 days. Neutrophil phagocytosis was suppressed by the lesion,
The effect of venlafaxine treatment on the behavioural and neurochemical changes in the olfactory bulbectomised rat
โ Scribed by C. McGrath; T. R. Norman
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 316 KB
- Volume
- 136
- Category
- Article
- ISSN
- 0033-3158
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The anterior olfactory nucleus (AON) is located caudal to the olfactory bulb in the olfactory peduncle. Although this important structure is involved in the bilateral coordination of olfactory information, relatively little is known about its development, structure, or function. The present report d