Continuous production of a recombinant murine granulocyte-macrophage colony-stimulating factor (MuGM-CSF) by immobilized yeast cells, Saccharomyces cerevisiae strain XV2181 (a/a, Trpl) containing plasmid paADH2, in a fluidized bed bioreactor was studied at a 0.03 h-' dilution rate and various partic
The effect of tracer diffusion on liquid axial dispersion in a three phase fluidized bed bioreactor
β Scribed by V.S. Thompson; R.M. Worden
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 490 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0009-2509
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β¦ Synopsis
Particle Peclet numbers ranging from 0.056-O. 198 were calculated from tracer response measurements in a three-phase fluid&d bed consisting of air, water, and alginate beads. Diffusion of the calcium chloride tracer into the beads was measured and found to follow Fick's Law. If unaccounted for, intraparticle tracer difision was shown to cause a 20% underprediction of Peclet number.
π SIMILAR VOLUMES
intersections when the values of \(B\) and \(\alpha^{\prime}\) are higher than 1 , i.e. when the deactivation is so high that the functional availability of the reactor volume is not completely achieved. The maximum values of \(z_{A P} / z_{A M}\) for \(B\) and \(\alpha^{\prime}\) less than 1 are a