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The effect of tolcapone on levodopa pharmacokinetics is independent of levodopa/carbidopa formulation

✍ Scribed by K. Jorga; Barbel Fotteler; Greg Sedek; Thorkild Nielsen; John Aitken


Publisher
Springer
Year
1998
Tongue
English
Weight
115 KB
Volume
245
Category
Article
ISSN
0340-5354

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The aim of our study was to evaluate the influence of low-intensity exercise on levodopa absorption and levodopa motor effect. We studied the pharmacokinetics and pharmacodynamics of levodopa under resting conditions and under a workload of 50 watts for 2 hours on a cycle ergometer in 12 parkinsonia