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The effect of thiopental on glutamate metabolism in mousecerebellar astrocytes in vitro

✍ Scribed by Hong Qu; Maurits van der Gaag; Thierry Le Maire; Ursula Sonnewald


Book ID
117471708
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
121 KB
Volume
304
Category
Article
ISSN
0304-3940

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3-Nitropropionic acid (3-NPA) is a selective and irreversible inhibitor of succinate dehydrogenase. The effect of this compound on the metabolism of [U-13 C]glutamate was studied in astrocytes using 13 C nuclear magnetic resonance spectroscopy. The appearance of [1,2,3-13 C]glutamate in cell extract