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The effect of thalidomide on neovascularization in a mouse model of retinopathy of prematurity

โœ Scribed by Ronen Rabinowitz; Gabriel Katz; Mordechai Rosner; Sara Pri-Chen; Abraham Spierer

Publisher
Springer-Verlag
Year
2008
Tongue
English
Weight
314 KB
Volume
246
Category
Article
ISSN
0065-6100

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## Abstract Vascular endothelial growth factor (VEGF) plays a central role in vasoproliferative diseases in the retina, however, other gene products modulate its effects. The angiopoietins are particularly important in this regard. Angiopoietin 2 (Ang2) collaborates with VEGF to stimulate neovascul