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Geldanamycin treatment reduces neovascularization in a mouse model of retinopathy of prematurity

โœ Scribed by Norbert Kociok; Tim U. Krohne; Vassiliki Poulaki; Antonia M. Joussen


Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
407 KB
Volume
245
Category
Article
ISSN
0065-6100

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Angiopoietin 1 prevents retinal detachme
โœ Hiroyuki Nambu; Naoyasu Umeda; Shu Kachi; Yuji Oshima; Hideo Akiyama; Rie Nambu; ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 450 KB

## Abstract Vascular endothelial growth factor (VEGF) plays a central role in vasoproliferative diseases in the retina, however, other gene products modulate its effects. The angiopoietins are particularly important in this regard. Angiopoietin 2 (Ang2) collaborates with VEGF to stimulate neovascul