A 2 Γ 2 factorial design was performed to determine the effect of a permeation enhancer (oleic acid/propylene glycol), iontophoresis (2 V), and the combination of the two treatments on the permeation enhancement of a model peptide, LHRH (luteinizing hormone releasing hormone), through human epiderma
The effect of temperature upon the permeation of polar and ionic solutes through human epidermal membrane
β Scribed by Kendall D. Peck; Abdel-Halim Ghanem; William I. Higuchi
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 986 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Known descriptors for ions and ionic species (deprotonated carboxylic acid anions and protonated base cations) can be combined with descriptors for neutral species to obtain a general equation for permeation from saline through the blood-brain barrier. The equation can be used to indicate the compou
The present study investigated the effects of oxygen-containing terpenes as skin permeation enhancers on the lipoidal pathways of human epidermal membrane (HEM). The enhancement (E(HEM)) effects of menthol, thymol, carvacrol, menthone, and cineole on the transport of a probe permeant, corticosterone
Thermosensitive membranes with high mechanical strength were prepared by heterogeneous graft copolymerization of N-isopropylacrylamide (NIPAAm) onto cellophane in a nitric acid solution using cerium ammonium nitrate as an initiator, and the permeation behavior of solutes such as lithium chloride and
Thermosensitive copolymers were prepared by graft copolymerization of N-isopropylacrylamide onto poly(viny1 alcohol) in dimethyl sulfoxide (DMSO) using potassium peroxodisulfate as an initiator. The phase transition temperature was measured by differential scanning calorimetry. The copolymers exhibi
**As a probe for changes in hydrate structure** one can use the pressureβdependence of the activation volume Ξ__V__^β ^ for rotation of the Me~2~N group in dimethyl acetamide (DMA). In dilute solutions Ξ__V__^β ^ for DMA is practically pressureβindependent, but is increased by ionic solutes. This coul