## Abstract The effect of serum on the growth properties of nonβtransformed Balb 3T3 A31 and SV40βtransformed Balb 3T3 A31 was studied. The concentration of serum in the growth medium of nonβtransformed cells had little effect on the initial population doubling time, but did regulate the cell densi
The effect of SV40 transformation on the chromosomal proteins of 3T3 mouse embryo fibroblasts
β Scribed by M.O. Krause; K.D. Noonan; L.J. Kleinsmith; G.S. Stein
- Book ID
- 113209981
- Publisher
- Elsevier Science
- Year
- 1976
- Weight
- 725 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0045-6039
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π SIMILAR VOLUMES
Balb/c mouse embryo cultures that are carried under a rigid transfer schedule that minimizes cell-cell contact evolve into permanent lines that possess properties very similar to 3T3. From the same embryo cultures, a transfer schedule where cell-cell contact is extensive leads to lines (Balb/3T12) t
## Abstract Unlike untransformed 3T3 fibroblasts, Simian Virus 40βtransformed 3T3 cells (SV3T3) do not require the presence of exogenous polypeptide mitogens in order to become competent for the initiation of DNA synthesis. As an explanation for this state of perpetual competence, growth activity f