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The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure

โœ Scribed by Pitt, Bertram; Zannad, Faiez; Remme, Willem J.; Cody, Robert; Castaigne, Alain; Perez, Alfonso; Palensky, Jolie; Wittes, Janet

Book ID
121797631
Publisher
Massachusetts Medical Society
Year
1999
Tongue
English
Weight
192 KB
Volume
341
Category
Article
ISSN
0096-6762

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โœ Packer, Milton; Bristow, Michael R.; Cohn, Jay N.; Colucci, Wilson S.; Fowler, M ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Massachusetts Medical Society ๐ŸŒ English โš– 140 KB

## Background: Controlled clinical trials have shown that beta-blockers can produce hemodynamic and symptomatic improvement in chronic heart failure, but the effect of these drugs on survival has not been determined. ## Methods: We enrolled 1094 patients with chronic heart failure in a double-bli