Cost-effectiveness of spironolactone in patients with severe heart failure
โ Scribed by L Tilson; B McGowan; M Ryan; M Barry
- Publisher
- Springer-Verlag
- Year
- 2003
- Tongue
- English
- Weight
- 344 KB
- Volume
- 172
- Category
- Article
- ISSN
- 1863-4362
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Angiotensin converting enzyme inhibitors have greatly improved the treatment of patients with chronic heart failure but they are not effective in all patients, and their use may be limited by side effects. There is, therefore, a need to investigate new drugs and to compare their efficacy with angiot
Twenty patients (5 females, 15 males) with severe heart failure (NYHA IV), due to coronary artery disease in 14, and congestive cardiomyopathy in 6, received an intravenous bolus of the calcium blocker nisoldipine 0.2 mg followed by a continuous infusion of 0.2 micrograms.kg-1.min-1. Haemodynamic me