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The Effect of Solvent on a Lewis Acid Catalyzed Diels−Alder Reaction, Using Computed and Experimental Kinetic Isotope Effects

✍ Scribed by Acevedo, Orlando; Evanseck, Jeffrey D.


Book ID
127325585
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
119 KB
Volume
5
Category
Article
ISSN
1523-7060

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✍ Daniel A. Singleton; Steven R. Merrigan; Brett R. Beno; K.N. Houk 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 289 KB

2H and 13C kinetic isotope effects were determined for all positions on isoprene in its reactions with methyl vinyl ketone, ethyl acrylate, and acrolein catalyzed by Et2AICI. The results are taken as supporting a highly asynchronous concerted [4+2] cycloaddition. Comparison of the experimental isoto