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The effect of silyl substituted methotrexate in the treatment of experimental allergic encephalomyelitis in rats mediated by T-line cells

✍ Scribed by H. Przuntek; M.E. Westarp; M.L. Vohl; M. Gerlach; P. Jutzi; H. Wekerle

Book ID
118955796
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
731 KB
Volume
26
Category
Article
ISSN
0028-3908

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Experimental allergic encephalomyelitis
Experimental allergic encephalomyelitis (EAE): Role of B cell and T cell epitopes in the development of EAE in lewis rats
✍ G. A. Hashim; E. D. Day; E. Carvalho; A. Abdelaal πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 837 KB

Studies from our laboratory have shown that classical clinical and histological signs of experimental allergic encephalomyelitis (EAE) may be induced in Lewis rats by synthetic peptides S49 or S55. Peptides S49S and S55S are defined by residues 69-84 and 72-84 of the guinea pig myelin basic protein