An internal Diels-Alder reaction, using furan as the diene component, formed a highly functionalized 5-membered carbocycllc ring in excellent yield. Solvent and substituent effects of this reaction were examined. In connection with a proJect devoted to the synthesis of some natural products contai
The effect of side chain substituents on the intramolecular diels-alder reaction of the furan diene: the synthesis of (±)-1,4-epoxycadinane
✍ Scribed by Christine Rogers; Brian A. Keay
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 296 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The effect of side chain substituents on the Intramolecular Diels-Alder reaction of the Furan diene (IMDAF) is reported in which the side chain connecting the furan diene to the dienophile contain four carbon atoms. The synthesis of 1,4epoxycadinane
📜 SIMILAR VOLUMES
A variety of substituted furans a-6J undergo the intramolecular Die&Alder reaction at high pressure (12.5 kbar) to provide oxatricyclo adducts Q-12) within 24 hours at room temperature.
## Abstract Seven alkyl and aryl substituted __N__‐allyl‐__N__‐(methylfuran)‐sulfonamide compounds have been synthesized and their rates of cyclization and equilibrium product concentrations determined. Increased steric bulk on the sulfonamide substituent has been shown to increase both the rate of