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The Effect of Selective Cyclooxygenase Inhibitors on Intestinal Epithelial Cell Mitogenesis

✍ Scribed by Brian A. Erickson; Walter E. Longo; Ninder Panesar; John E. Mazuski; Donald L. Kaminski

Book ID
115635777
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
140 KB
Volume
81
Category
Article
ISSN
0022-4804

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## Abstract As with cyclooxygenase (COX)‐2, genetic disruption of __COX‐1__ gene or pharmacologic inhibition of its activity has been shown to decrease the number of intestinal polyps in __Apc__ gene‐deficient mice. The present study was designed to investigate the combined effects of COX‐1 and COX