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The effect of salicylate on the biliary excretion of 14C-bishydroxycoumarin in rat

โœ Scribed by H. S. BUTTAR; B. B. COLDWELL; B. H. THOMAS


Book ID
117956341
Publisher
Nature Publishing Group
Year
1973
Tongue
English
Weight
994 KB
Volume
48
Category
Article
ISSN
0007-1188

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In vivo biotransformation and biliary ex
โœ B. I. Ghanayem; A. E. Ahmed ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 536 KB

1-14C-Acrylonitrile (VCN) was given orally to rats, 27% of the given dose was excreted in bile in 6 h. When 1-14C-VCN was given to overnight fasted or cobaltous chloride treated rats, a significant increase in the biliary excretion occurred. Pretreatment of rats with phenobarbital produced no change