𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The effect of prednisolone on the foetotoxicity of cadmium in pregnant mice

✍ Scribed by A. Selypes; R. Lorencz; G. Berencsi; I. Dési

Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
202 KB
Volume
6
Category
Article
ISSN
0260-437X

No coin nor oath required. For personal study only.

✦ Synopsis

The effects of prednisolone was investigated on the foetotoxicity of cadmium. CFLP female mice were given a single i.p. dose of 2.5 mg cadmium (Cd) per kg body weight on day 5 or 9 of gestation. This treatment significantly decreased both the number of live foetuses and foetal weights on day 18 of gestation. Prednisolone (0.1 mg kg-') given daily from the day of cadmium treatment death, prevented the effects of cadmium on foetal weights in both groups, and on the number of live foetuses when cadmium was given on day 9 of gestation. When Cd was given on day 13 of gestation similar treatment with prednisolone did not influence either litter size or the weights of 1-day-old pups.

📜 SIMILAR VOLUMES

The preventive effect of prednisolone on
The preventive effect of prednisolone on the adrenal toxicity of cadmium
✍ A. Selypes; R. Lorencz; P. Serényi 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 173 KB 👁 1 views

The effects of a single dose of 3.3 mg/kg body weight i.p. or of a single dose of 0.2 mg/kg per 0s of cadmium and prednisolone on the adrenal weight and the thickness of the adrenal cortex were investigated in female mice. A significant increase was detected in the mean weight of the adrenals and th

Effect of Selenium Supplementation on th
Effect of Selenium Supplementation on the Glutathione Redox System in the Kidney of Mice after Chronic Cadmium Exposures
✍ Leelank B. Nehru; M. P. Bansal 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 84 KB 👁 2 views

This study pertains to the role of selenium against the toxic manifestations of chronic cadmium exposure. The kidney is a recognized target organ for chronic cadmium exposure, owing to the very long halflife of cadmium. Cadmium (as cadmium chloride) in a dose of 8 mg kg ؊1 body wt. was administered