The effect of poloxamer 188 on nanoparticle morphology, size, cancer cell uptake, and cytotoxicity

✍ Scribed by Fei Yan; Chao Zhang; Yi Zheng; Lin Mei; Lina Tang; Cunxian Song; Hongfan Sun; Laiqiang Huang

• Book ID: 104063110
• Publisher: Elsevier Science
• Year: 2010
• Tongue: English
• Weight: 701 KB
• Volume: 6
• Category: Article
• ISSN: 1549-9634
• DOI: 10.1016/j.nano.2009.05.004

✦ Synopsis

From the clinical editor:

The effects of poloxamer 188, a triblock copolymer were studied on nanoparticle morphology, size, cancer cell uptake and cytotoxicity. an increased level of uptake of plga/poloxamer 188 nanoparticles in resistant human breast cancer cell line was demonstrated, resulting in a significantly higher level of cytotoxicity.