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The effect of pedigree structure on detection of deletions and other null alleles

✍ Scribed by Johansson, Anna M; Säll, Torbjörn


Book ID
109848929
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
160 KB
Volume
16
Category
Article
ISSN
1018-4813

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## Abstract The asymptotic distribution of [MOD] scores under the null hypothesis of no linkage is only known for affected sib pairs and other types of affected relative pairs. We have extended the GENEHUNTER‐MODSCORE program to allow for simulations under the null hypothesis of no linkage to deter