The effect of mouse interferon on the transformation of NIH/3T3 mouse cells by murine sarcoma Virus
β Scribed by A.G. Morris; C. Clegg
- Book ID
- 119009715
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- English
- Weight
- 236 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0042-6822
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## Abstract Mousee interferon (IFN) was found to inhibit murine sarcoirus (MSV)induced neoplastic transformation of normal rat kidney (NRK) cells. This effect was observed upon examining the formation of foci of morphologically altered cells and colonies of anchorageβindependent cells. IFN had no c
This study reports high incidence tumourigenic activity of the pSV2neo plasmid demonstrated by transfection of NIH 3T3 cells. The plasmid is frequently used as a dominant selectable marker for confirming successful gene transfection, and the findings indicate a need for caution in interpretation and