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The effect of morphine, pimozide and naloxone on discrimination by rats in a shock escape test

✍ Scribed by Vahn A. Lewis; I.Cathy Liles

Book ID
118939958
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
369 KB
Volume
27
Category
Article
ISSN
0024-3205

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Blockade of the discriminative effects o
Blockade of the discriminative effects of morphine in the rat by naltrexone and naloxone
✍ Harlan E. Shannon; Stephen G. Holtzman πŸ“‚ Article πŸ“… 1976 πŸ› Springer 🌐 English βš– 589 KB

The capacity of the specific narcotic antagonists naltrexone and naloxone to block the discriminative effects produced by morphine in the rat were evaluated using a two-choice, discrete-trial avoidance task. The antagonists produced a dose-dependent and time-dependent blockade of morphine's effects