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Increase in the threshold of a nociceptive test induced by naloxone in morphine-tolerant rats

✍ Scribed by Valérie Kayser; Gisèle Guilbaud


Book ID
118870665
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
367 KB
Volume
344
Category
Article
ISSN
0006-8993

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In the rat, theophylline has been shown to potentiate the effect of morphine on the threshold for vocalisation after withdrawal of stimulation. This response to painful stimulation is considered to be integrated at the level of the thalamus-hypothalamus-rhinencephalon. Naloxone antagonized the effec