The Effect of Mechanical Loading on the Metabolism of Growth Plate Chondrocytes
β Scribed by Masashi Ueki; Nobuaki Tanaka; Kotaro Tanimoto; Clarice Nishio; Kobun Honda; Yu-Yu Lin; Yuki Tanne; Satoru Ohkuma; Takashi Kamiya; Eiji Tanaka; Kazuo Tanne
- Publisher
- Springer
- Year
- 2008
- Tongue
- English
- Weight
- 345 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0090-6964
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Growth plate chondrocytes isolated from the proliferative and hypertrophic zones of bovine costochondral junctions were grown in vitro in the presence of various oxygen tensions ranging from 3 to 60%. Using [^35^S] sulfate as an index of glycosaminoglycan synthesis, incorporation was fo
## Abstract Parathyroid hormoneβrelated peptide (PTHrP) and parathyroid hormone (PTH) have similar biological effects in vitro that are mediated through the PTH receptor. PTH receptors have been demonstrated in the zone of provisional calcification and the hypertrophic zone of the cartilaginous gro
## Abstract Bone elongation is predominantly driven by the volume expansion of growth plate chondrocytes. This mechanism was initially believed to be βhypertrophyβ, describing a proportional increase of cell water and organelles. However, morphometrical analysis subsequently assumed the increase to
## Abstract In the growth plate chondrocyte, parathyroid hormone (PTH) stimulates phosphoinositol 4, 5 bisphosphate (PIP~2~) degradation, which results in the rapid production of inositol (1,4,5) triphosphate (IP~3~). IP~3~ induced the release of calcium from an intracellular store, which caused a