The effect of solvent on permeant diffus
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Dias, M. (author);Hadgraft, J. (author);Raghavan, S. L. (author);Tetteh, J. (aut
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Article
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2004
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John Wiley and Sons Inc.
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English
β 441 KB
π 1 views
One method of improving the bioavailability of a topical formulation is to add an appropriate solvent that will act as a solubilizer for the permeant and, at the same time, modify the barrier properties of the stratum corneum. It has proved very difficult to determine the precise mechanisms of actio