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The effect of solvent on permeant diffusion through membranes studied using ATR-FTIR and chemometric data analysis

✍ Scribed by Dias, M. (author);Hadgraft, J. (author);Raghavan, S. L. (author);Tetteh, J. (author)


Publisher
John Wiley and Sons Inc.
Year
2004
Tongue
English
Weight
441 KB
Volume
93
Category
Article
ISSN
0022-3549

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The effect of solvent on permeant diffus
✍ Dias, M. (author);Hadgraft, J. (author);Raghavan, S. L. (author);Tetteh, J. (aut πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons Inc. 🌐 English βš– 441 KB πŸ‘ 1 views

One method of improving the bioavailability of a topical formulation is to add an appropriate solvent that will act as a solubilizer for the permeant and, at the same time, modify the barrier properties of the stratum corneum. It has proved very difficult to determine the precise mechanisms of actio