The effect of ionizing irradiation on the intraductal pressure of the human parotid gland
β Scribed by C.H. Hakansson; M. Lipecki; N.G. Toremalm
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 549 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0360-3016
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## Abstract ## Background. Xerostomia is caused by irradiation for head and neck cancer, depending on the dose to the parotid gland. To investigate which part of the parotid gland has to be spared with radiotherapy, detailed information about the vascular supply of the parotid gland is necessary.
Saline or BSA were instilled 2, 5, 8 or 11 times at daily intervals into the parotid glands of rats, via Stensen's duct. Hydropic change of the acinar cells developed after 8 and 11 instillations. Histologically, the lesion was characterized by enlargement of the acinar cells, the cytoplasm of which