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Acinar cell hydropic degeneration induced by intraductal instillation of solutions into the parotid glands of the rats

✍ Scribed by J. Sela; D. Schechter; E. Rosenmann; J. H. Boss

Publisher: Springer
Year: 1977
Tongue: English
Weight: 895 KB
Volume: 374
Category: Article
ISSN: 1432-2307
DOI: 10.1007/bf00430570

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✦ Synopsis

Saline or BSA were instilled 2, 5, 8 or 11 times at daily intervals into the parotid glands of rats, via Stensen's duct. Hydropic change of the acinar cells developed after 8 and 11 instillations. Histologically, the lesion was characterized by enlargement of the acinar cells, the cytoplasm of which contained vacuoles displacing the nuclei. In view of the negative results of various histochemical reactions the vacuolization was interpreted as hydropic in nature.

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