## Abstract An __in vitro__ study was performed to compare the effects of augmenting interlocking nails of one of two diameter (5 or 6 mm) with intramedullary polymethylmethacrylate. Subsequently, an __in vivo__ study was performed to compare the effects of augmenting the interlocking nail with fiv
The effect of intramedullary polymethylmethacrylate on healing of intercalary cortical allografts in a canine model
β Scribed by Dr. R. C. Straw; B. E. Powers; S. J. Withrow; M. F. Cooper; A. S. Turner
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 532 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0736-0266
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
The purpose of this study was to evaluate the effect of intramedullary polymethylmethacrylate (PMMA) bone cement on the healing of intercalry allografts. Thirteen adult beagles had bilateral intercalary femoral allografts implanted. The medullary canal of one randomly assigned allograft in each dog was filled with PMMA. Healing was followed clinically and femora were evaluated radiographically, biomechanically, histologically, and histomorphometrically 9 months after surgery. There was an increased percent of eroded surface at the endosteal area of the center region of grafts containing PMMA and there was an increased percent osteoblast surface in this area in grafts not containing PMMA. There was an increased percent eroded surface at the periosteal area in the center region in grafts not containing PMMA and there was an increased percent osteoblast surface at the periosteal area in the graft adjacent to the host junction in grafts containing PMMA. There was no significant difference between PMMAβtreated and untreated allografts in any other parameters measured. The results from this study suggest that, although the pattern of incorporation is altered, intramedullary PMMA does not appear to effect allograft healing adversely.
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