The effect of interferon alpha on myeloproliferation and vascular complications in polycythemia vera
✍ Scribed by N. Heis; C. Rintelen; B. Gisslinger; P. Knöbl; K. Lechner; H. Gisslinger
- Book ID
- 114792480
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 466 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0902-4441
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We studied the effects of recombinant interferon alpha-2a (IFN-alpha) in 36 patients with polycythemia Vera (PV) previously treated with phlebotomy and/or conventional cytostatic agents. In each patient, after at least 2 months of discontinuation of any cytotoxic therapy, the hematocrit (Hmt) was fi
We periodically analyzed bone-marrow cytogenetic features in 8 patients belonging to a series of 38 subjects with polycythemia vera (PV), all treated with recombinant interferonalpha 2a (rIFN-alpha) at a weekly dose of 9,000,000 IU. Six out of these 8 patients never showed any chromosome alterations