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The effect of inhibition of endothelial cell cyclooxygenase on arterial thrombosis

✍ Scribed by R.H. Bourgain; R. Andries; P. Braquet; C. Deby


Book ID
119050165
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
393 KB
Volume
30
Category
Article
ISSN
0090-6980

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Selective inhibition of cyclooxygenase (
✍ Kentaro Yazawa; Nelson H. Tsuno; Joji Kitayama; Kazushige Kawai; Yurai Okaji; Ma πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 336 KB

High-level expression of cyclooxygenase (COX)-2 is reported in 80 -90% of colorectal adenocarcinomas. Selective inhibition of COX-2 was shown to reduce colorectal tumorigenesis in different models of carcinogenesis and to prevent metastasis in xenograft tumor models, as well as to suppress in vitro