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Inhibition of cyclooxygenase (COX)-2 affects endothelial progenitor cell proliferation

✍ Scribed by Daniela Colleselli; Klaudija Bijuklic; Birgit A. Mosheimer; Christian M. Kähler

Book ID
118506445
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
395 KB
Volume
312
Category
Article
ISSN
0014-4827

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Selective inhibition of cyclooxygenase (COX)-2 inhibits endothelial cell proliferation by induction of cell cycle arrest
✍ Kentaro Yazawa; Nelson H. Tsuno; Joji Kitayama; Kazushige Kawai; Yurai Okaji; Ma 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 336 KB

High-level expression of cyclooxygenase (COX)-2 is reported in 80 -90% of colorectal adenocarcinomas. Selective inhibition of COX-2 was shown to reduce colorectal tumorigenesis in different models of carcinogenesis and to prevent metastasis in xenograft tumor models, as well as to suppress in vitro