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The effect of gp120 on morphine’s antinociceptive and neurophysiological actions

✍ Scribed by Xiaohong Chen; Lynn G. Kirby; Jonathan Palma; Khalid Benamar; Ellen B. Geller; Toby K. Eisenstein; Martin W. Adler

Book ID
116277163
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
458 KB
Volume
25
Category
Article
ISSN
0889-1591

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Effect of midbrain raphe lesion on the a
Effect of midbrain raphe lesion on the antinociceptive action of morphine and other analgesics in rats
✍ R. Samanin; D. Ghezzi; C. Mauron; L. Valzelli 📂 Article 📅 1973 🏛 Springer 🌐 English ⚖ 267 KB

The antinociceptive action of several analgesics was studied by two methods: the hot-plate and the tail compression tests. Lesions of the midbrain raphe, which produce a marked depletion of serotonin in the forebrain, antagonize the analgesic effect of morphine but not that of methadone, meperidine