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The Effect of Glycosylation on the Folding Kinetics of Erythropoietin

โœ Scribed by Douglas D. Banks


Book ID
116664669
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
967 KB
Volume
412
Category
Article
ISSN
0022-2836

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โœ M. Yang; M. Butler ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 258 KB ๐Ÿ‘ 3 views

The effect of ammonium chloride was determined on a culture of CHO cells transfected with the human erythropoietin (EPO) gene. Cell growth was inhibited above a culture concentration of 5 mM NH 4 Cl with an IC-50 determined to be 33 mM. The specific production of EPO increased with the addition of N