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The effect of epidermal pigmentation on selective vascular effects of pulsed laser

✍ Scribed by Dr. O. T. Tan; Russell Kerschmann; John A. Parrish

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
625 KB
Volume
4
Category
Article
ISSN
0196-8092

No coin nor oath required. For personal study only.

✦ Synopsis

The effect of epidermal pigmentation on the threshold exposure dose for inducing purpura with a tunable dye laser at 577 nm, 1.5 1 s pulse duration, was studied in 2 I human volunteers with varied genetically determined amounts of melanin. More laser energy was required to produce purpura as constitutive skin pigmentation increased. Histology showed that, in lighter skin, the laser threshold dose produced the most specific vascular injury with no disruption of surrounding structures. In more pigmented skin, damage occurred in the epidermal basal layer and very few changes were seen in blood vessels below.

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