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The effect of dietary imbalances on the activation of benzo[a]pyrene by the metabolizing enzymes from rat liver

✍ Scribed by P. Cassano; D. Bonnamour; P. Grolier; M.A. Pelissier; Z. Amelizad; R. Albrecht; J.F. Narbonne

Book ID
113255023
Publisher
Elsevier Science
Year
1987
Weight
435 KB
Volume
191
Category
Article
ISSN
0165-7992

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✍ Ronald A. Lubet; Jorge Capdevila; Russell A. Prouoh πŸ“‚ Article πŸ“… 1979 πŸ› John Wiley and Sons 🌐 French βš– 473 KB πŸ‘ 1 views

## Abstract A rat liver microsome‐mediated bacterial mutagenicity test showed 9‐hydroxybenzo (__a__) pyrene to be significantly more effective as a pre‐mutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex