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The effect of cyclopentenyl cytosine on human sk-n-be (2)-C neuroblastoma cells

✍ Scribed by Robbert J. Slingerland; Albert H. Van Gennip; Jeroen M. Bodlaender; P.A. Voûte; AndréB.P. Van Kuilenburg

Book ID
115784207
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
303 KB
Volume
50
Category
Article
ISSN
0006-2952

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## Abstract CPEC is a potent inhibitor of CTP synthetase and causes depletion of CTP and dCTP pools. AraC is an analog of dCyd and a chemotherapeutic agent. Here, we demonstrate that, upon incubation with CPEC, both the anabolism and cytostatic effect of AraC in SK‐N‐BE(2)c neuroblastoma cells were