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The effect of combination treatment with gemcitabine and the EGFR-receptor tyrosine kinase inhibitor iressa with photodynamic therapy in bladder cancer

✍ Scribed by C.H. Briggs; C.D. Betts; K.J. O'Flynn; J.V. Moore; N.W. Clarke


Book ID
118644328
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
200 KB
Volume
2
Category
Article
ISSN
1569-9056

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Overexpression of the growth factor receptors EGFR and erbB2 occurs frequently in several human cancers and is associated with aggressive tumour behaviour and poor patient prognosis. We have investigated the effects of ZD1839 (Iressa), a novel EGFR tyrosine kinase inhibitor, on the growth, in vitro