The effect of chronic morphine administration on proliferation of murine splenocytes
β Scribed by D.B. Couch; W.B. Lushbaugh
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 99 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0192-0561
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The disposition of morphine (MOR) and its metabolites in the rabbit was measured after topical administration of its hydrochloride salt (MOR. HCI), and their time course was compared with those after intravenous and oral administration. The area under the plasma concentration-time curve (AUC) ratio
## Abstract We have shown that the murine lymphoblast, L5178Y, requires extracellular magnesium or calcium for proliferation in suspension culture. Although both cations produce biphasic effects on growth, magnesium is the more potent since it: (1) stimulates proliferation at lower concentrations;