## Abstract This study demonstrates a synergistic effect of IFNฮณ and PMA on superoxide generation by human monocytes. A strict correlation was observed between the induction of superoxide production and PKโC activation by PMA alone. No such correlation was evident for IFNฮณ. However, exposure of the
Synergistic effect of phorbol myristate acetate on bacterial lipopolysaccharide induced rat splenocyte proliferation
โ Scribed by H. Xu; L.F. Lau; C.M. Lee
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 378 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0020-711X
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๐ SIMILAR VOLUMES
The effect of phorbol 12-myristate 13-acetate (PMA) on Ca2+-ATPase activity in rat h e r nuclei was investigated. Ca2 +-ATPase activity was calculated by subtracting Mg2+ -ATPase activity from (Ca2 +-Mg2 +)-ATPase activity. The nuclear Ca2+-ATPase activity was significantly increased by the presence
The effects of phorbol myristate acetate (PMA) and dexamethasone on protein kinase C (PK-C) activity and eicosanoid production were characterized in primary cultures of rat glial cells. PMA (1,000 ng/ml) treatment for 2 hr resulted in a maximal effect (a 4-fold increase in PGE, production). Longer e