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The Effect of Aprotic Dipolar Organic Solvents on the Kinetics of α-Chymotrypsin-Catalyzed Hydrolyses *

✍ Scribed by Clement, Gerald E.; Bender, Myron L.

Book ID
126162077
Publisher
American Chemical Society
Year
1963
Tongue
English
Weight
1006 KB
Volume
2
Category
Article
ISSN
0006-2960

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Effect of water-miscible aprotic solvent
Effect of water-miscible aprotic solvents on kyotorphin synthesis catalyzed by immobilized α-chymotrypsin
✍ Pedro Lozano; Teresa Diego; José L. Iborra 📂 Article 📅 1995 🏛 Springer Netherlands 🌐 English ⚖ 353 KB

Immobilized a-chymotrypsin was used as catalyst to synthesize a kyotorphin derivative (Bz-Tyr-Arg-OEt) in the presence of five water-miscible aprotic solvents (dimethylsulphoxide, dimethylformamide, acetonitrile, acetone and tetrahydrofurane) at 30 °C. By using a kineticallycontrolled approach, the