A sensitive and specific LC-MS/MS assay for the determination of paclitaxel and its 3'p- and 6-alpha-hydroxy metabolites is presented. A 200 microL plasma aliquot was spiked with a 13C6-labeled paclitaxel internal standard and extracted with 1.0 mL tert-butylmethylether. Dried extracts were reconsti
The effect of alkylamine additives on the sensitivity of detection for paclitaxel and docetaxel and analysis in plasma of paclitaxel by liquid chromatography–tandem mass spectrometry
✍ Scribed by Songmei Gao; Zong-Ping Zhang; L. E. Edinboro; Lambert C. Ngoka; H. T. Karnes
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 372 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0269-3879
- DOI
- 10.1002/bmc.582
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