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The effect of aging on sister chromatid exchange

✍ Scribed by Edward L. Schneider; David Kram; Yoshifumi Nakanishi; Robert E. Monticone; Raymond R. Tice; Brian A. Gilman; Michael L. Nieder

Book ID: 119025030
Publisher: Elsevier Science
Year: 1979
Tongue: English
Weight: 648 KB
Volume: 9
Category: Article
ISSN: 0047-6374
DOI: 10.1016/0047-6374(79)90107-6

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Although baseline levels of SCE appear to be similar in metaphase cells derived from young and old human skin fibroblast cultures, a significant decline in both MMC- and AAAF-induced sister chromatid exchanges was observed in the older cell populations. Considerable variation exists in the levels of