The effect of actinomycin on the synthesis of mitochondrial RNA in hamster cells
β Scribed by Dubin, Donald T.
- Book ID
- 122422854
- Publisher
- Elsevier Science
- Year
- 1967
- Tongue
- English
- Weight
- 301 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0006-291X
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Anthramycin and actinomycin D, two different types of DNAbinding antibiotics, were compared for their effects on RNA synthesis in suspension cultures of mouse leukemia L1210 cells. RNA was labeled with radioactive uridine and selective effects on the synthesis of different classes of RNA were studie
RNA synthesis was studied by autoradiographic analysis using tritiated uridine incorporation in the Chinese hamster cell line Dede after a one-minute pulse labeling period. RNA synthesis continues during all stages of interphase and mitosis except during metaphase and anaphase. Cytoplasmic RNA was a