## Abstract Acrolein (Acr) is a ubiquitous environmental contaminant; it also can be generated endogenously by lipid peroxidation. Acr contains a carbonyl group and an olefinic double bond; it can react with many cellular molecules including amino acids, proteins and nucleic acids. In this review a
The effect of acrylamide on hepatocellular dna repair
โ Scribed by Miller, Mary Jo ;McQueen, Charlene A.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1986
- Weight
- 505 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0192-2521
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Complex multicellular organisms have evolved mechanisms to ensure that individual cells follow their proper developmental and somatic programs. Tumorigenesis, or uncontrolled cellular proliferation, is caused by somatic mutations to those genetic constraints that normally operate within a tissue. Ge
## Abstract To determine whether variations in DNA repair genes are related to host DNA damage, we investigated the association between polymorphism in the __XPD__ gene (codon 199, 312, 751) and the __XRCC1__ gene (codon 194, 399) and the presence of benzo(a)pyrene diolepoxide adducts to lymphocyte