𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Repair of DNA double-strand breaks and its effect on RBE

✍ Scribed by D. Frankenberg


Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
914 KB
Volume
14
Category
Article
ISSN
0273-1177

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Hypothesis: transcript-templated repair
✍ Deborah A. Trott; Andrew C.G. Porter πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 155 KB πŸ‘ 2 views

## Abstract Two mechanisms are available for the repair of DNA double‐strand breaks (DSBs) in eukaryotic cells: homology directed repair (HDR) and non‐homologous end‐joining (NHEJ). While NHEJ is not restricted to a particular phase of the cell cycle, it is incapable of accurately repairing DBSs th

Nijmegen breakage syndrome: consequences
✍ Martin Digweed; AndrΓ© Reis; Karl Sperling πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 85 KB

The autosomal recessive genetic disorder, Nijmegen Breakage Syndrome, is characterised by an excessively high risk for the development of lymphatic tumours and an extreme sensitivity towards ionising radiation. The most likely explanation for these characteristics, a deficiency in the repair of DNA

The cellular control of DNA double-stran
✍ Shaun P. Scott; Tej K. Pandita πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 283 KB πŸ‘ 1 views

## Abstract DNA double‐strand breaks (DSBs) are the most hazardous lesions arising in the genome of eukaryotic organisms, and yet occur normally during DNA replication, meiosis, and immune system development. The efficient repair of DSBs is crucial in maintaining genomic integrity, cellular viabili

Double-strand breaks in DNA caused by re
✍ Bradley, Matthews O. πŸ“‚ Article πŸ“… 1981 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 341 KB πŸ‘ 1 views

## Abstract DNA DSBs are formed in normal human IMR‐90 cells during repair incubation after 100 and 300 JΒ·m^βˆ’2^ of UVL. By contrast, no DSBs are formed after UVL in human XPA cells that are unable to excise pyrimidine dimers. The DSBs are not due to immediate cell death since all the cells excluded