✦ LIBER ✦

The effect of a brain lesion on bone healing

✍ Scribed by R. F. Spencer; R. Bullock; K. Cooper; R. J. Norman; P. J. Becker

Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 487 KB
Volume: 8
Category: Article
ISSN: 0736-0266
DOI: 10.1002/jor.1100080505

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Using a feline model, the effects of stereotaxic brain lesions producing unilateral spasticity on bilateral fibular osteotomies were observed. Healing in spastic limbs occurred with more new bone formation than on the contralateral (control) side. Union appeared to be slightly faster in spastic limbs. Histomorphometric analysis of resected fibular specimens following union revealed little difference between spastic and non‐spastic limbs. When these brain‐lesioned animals were compared with a group with identical osteotomies but no brain lesions in respect of various systemic biochemical and endocrine parameters, no differences were found.

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