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The effect of 6-mercaptopurine on the total acid-soluble and nucleic acid adenine and guanine nucleotides of Ehrlich ascites tumour cells

✍ Scribed by A.W. Murray

Book ID
115742411
Publisher
Elsevier Science
Year
1966
Weight
120 KB
Volume
123
Category
Article
ISSN
0005-2787

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o Molephantinin, a germacranolide, has previously been shown to possess antineoplastic activity in rodents. The principle effect of molephantinin on Ehrlich ascites carcinoma cells was to depress DNA and protein synthesis both in uiuo and in uitro. DNA synthesis was inhibited a t the following sites