The effect of 5-hydroxytryptamine and 5-hydroxytryptophan on extra-pyramidal function
✍ Scribed by S. Hadžović; A.M. Ernst
- Book ID
- 118320346
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- English
- Weight
- 372 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0014-2999
No coin nor oath required. For personal study only.
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The effects of 5-hydroxytryptamine and 5-hydroxytryptophan on insulin release and 45Ca2+ uptake in islets microdissected from ob/ob mice were studied. At a concentration of 4 mmol/l both compounds slightly stimulated insulin release at a low glucose concentration (3 mmol/l). Insulin release induced
The kynurenine pathway metabolites kynurenine, 3-hydroxykynurenine and xanthurenic acid have been tested against 5-hydroxytryptamine (5-HT) and 5-hydroxytryptophan (5-HTP)-induced head twitches in the mouse in a dose-range of 0.5-5.0 mg/ kg. Kynurenine and 3-hydroxykynurenine were highly active. Low