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The effect of 3-palmitoyl-(+)-catechin on kupffer cells in guinea pig liver

✍ Scribed by Professor; Chairman Marcello Piazza; Guglielmo Borgia; Jane Crowell; Salvatore Nappa; Alberto Lambiase; Daniel Perrissoud; Werner Schreil

Publisher: John Wiley and Sons
Year: 1985
Tongue: English
Weight: 359 KB
Volume: 5
Category: Article
ISSN: 0270-9139
DOI: 10.1002/hep.1840050527

No coin nor oath required. For personal study only.

✦ Synopsis

We report a morphometric study on the effect of 3-palmitoyl-(+)-catechin on phagocytic activity of latex particles by Kupffer cells in guinea pig liver. We found an increase in the density of latex particles in Kupffer cells of animals treated with 3-palmitoyl-(+)-catechin. The volume and density of Kupffer cells of treated animals increased (p e 0.01); there was no significant difference in surface density of the plasma membrane. None of the parameters measured was altered in endothelial cells. These results show that 3-palmitoyl-(+)-cathin produces morphological and functional changes in Kupffer cells.

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