๐”– Bobbio Scriptorium
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The early involvement of chaperones in tau pathogenesis

โœ Scribed by Chad A. Dickey; John C. O'Leary; Sergiy Borysov; John Koren; Jeffrey Jones; Lisa Lawson; Laura Blair; Ying Jin; Lisa Lawson; Jose F. Abisambra; Qingyou Li; Umesh K. Jinwal


Book ID
118466692
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
41 KB
Volume
6
Category
Article
ISSN
1552-5260

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Chaperone-mediated autophagy (CMA) contributes to selective degradation of individual soluble proteins in lysosomes. Unique to this type of autophagy is the fact that proteins reach the lysosomal lumen for degradation by directly crossing the lysosomal membrane, in contrast with the vesicle-mediated